| date | topic | notes | homework | recommended readings |
|---|---|---|---|---|
| Major Unit. Genomics Foundations: Modeling and Measuring Evolution: Linkage Disequilibrium (LD), Urn Models | ||||
| Sept. 4 | ||||
| Sept. 9 | ||||
| Sept. 11 | ||||
| Major Unit. Genome-Wide Association Studies (GWAS): Statistical associations, the missing heritabililty problem, genetic heterogeneity, genomic privacy. | ||||
| Sept. 16 | ||||
| Sept. 18 | ||||
| Sept. 23 | ||||
| Major Unit. The Social Network of Protein Folds: Individual Preferences of Amino Acids and the Thermodynamic "Social Choice" Hypothesis | ||||
| Sept. 25 | ||||
| Sept. 30 | ||||
| Oct. 2 | ||||
| Major Unit. Algorithms: Maximum Likelihood and Expectation-Maximization Algorithms: Inferring haplotype frequencies in populations. | ||||
| Oct. 7 | ||||
| Oct. 9 | ||||
| Oct. 14 | ||||
| Major Unit. Algorithms: Set-cover and Minimum Informative Subset Algorithms: Tagging SNPs selection, LD. | ||||
| Oct. 16 | ||||
| Oct. 21 | ||||
| Oct. 23 | ||||
| Major Unit. Algorithms: Graph-Theory Algorithms: Haplotype Phasing, Haplotype Assembly, Identical-by-Descent Inference | ||||
| Oct. 28 | ||||
| Oct. 30 | ||||
| Nov. 4 | ||||
| Major Unit. Algorithms: Markov Chain Monte Carlo Algorithms: Population Substructure | ||||
| Nov. 6 | ||||
| Nov. 11 | ||||
| Nov. 13 | ||||
| Major Unit. Algorithms: Statistical Hypothesis Testing and Knapsack Algorithms: The Neyman-Pearson Lemma, Multiple Testing | ||||
| Nov. 18 | ||||
| Nov. 20 | ||||
| Nov. 25 | ||||
| Major Unit. Algorithms: Voting Theory Algorithms and von Neumann-Morgenstern Utility Theory: Protein Folding Energy Function Inference | ||||
| Nov. 27 | NO CLASS | NO CLASS | NO CLASS | NO CLASS |
| Dec. 2 | ||||
| Dec. 4 | ||||
| Dec. 9 | ||||